CGP-74514
Product Specifications
CAS Number
190653-73-7
Target
Apoptosis, CDK
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
0.9854
Bioactivity
CGP-74514 (Compound 13) is a highly selective cyclin-dependent kinase 1 (CDK1) inhibitor (IC50=25 nM) . This compound inhibits CDK1/cyclin B complex activity, resulting in G2/M phase cell cycle arrest and induction of tumor cell apoptosis, demonstrating promising applications in bladder cancer research.
Smiles
N(C1=C2C(N(CC)C=N2)=NC(N[C@@H]3[C@H](N)CCCC3)=N1)C4=CC(Cl)=CC=C4
Molecular Formula
C19H24ClN7
Molecular Weight
385.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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