SR-2890
Product Specifications
CAS Number
1454584-91-8
Target
Casein Kinase
Related Pathways
Stem Cells|||Metabolism
Purity
0.991
Bioactivity
SR-2890 is a potent and highly selective casein kinase 1?/1? (CK1?/?) inhibitor with an IC50 of 4 nM for CK1?. This compound inhibits melanoma A375 cell growth with an EC50 of 38 nM in MTT assays and possesses pharmacokinetic properties suitable for xenograft studies using human cancer cell lines.
Smiles
FC1=CC=CC(=C1)N2C=NC=3C(=NC(=NC32)N4CCNCC4)NCC5=NC=6C=CC(Cl)=CC6N5
Molecular Formula
C23H21ClFN9
Molecular Weight
477.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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