M4K2009
Product Specifications
CAS Number
2600795-07-9
Target
ALK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9857
Bioactivity
M4K2009 is a selective and brain-penetrant ALK2 inhibitor (IC50 = 13 nM) effective against both wild-type (WT) and mutant ALK2 (G328V, R206H, and R258G), used for the treatment of diffuse intrinsic pontine glioma (DIPG) .
Smiles
N1=CC(C2=CC=C(C=C2)N3CCNCC3)=C(C(=C1)C4=CC(OC)=C(OC)C(OC)=C4)C
Molecular Formula
C25H29N3O3
Molecular Weight
419.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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