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M4K2009

Product Specifications

CAS Number

2600795-07-9

Target

ALK

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Purity

0.9857

Bioactivity

M4K2009 is a selective and brain-penetrant ALK2 inhibitor (IC50 = 13 nM) effective against both wild-type (WT) and mutant ALK2 (G328V, R206H, and R258G), used for the treatment of diffuse intrinsic pontine glioma (DIPG) .

Smiles

N1=CC(C2=CC=C(C=C2)N3CCNCC3)=C(C(=C1)C4=CC(OC)=C(OC)C(OC)=C4)C

Molecular Formula

C25H29N3O3

Molecular Weight

419.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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