JNJ-9676
Product Specifications
CAS Number
3026520-19-1
Target
DNA/RNA Synthesis, SARS-CoV
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology
Purity
0.9993
Bioactivity
JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, which binds to the membrane protein dimer's transmembrane domain-formed binding pocket, thereby blocking viral assembly and release. It exhibits nanomolar-level antiviral activity against the novel coronavirus and SARS-CoV.
Smiles
C(NC1=CC(C#N)=CC=C1)(=O)C2=C3N(C[C@H](C)N(C3=O)C4=CC=C(C(F)(F)C5=CC=CC=C5)C=C4)N=C2
Molecular Formula
C28H21F2N5O2
Molecular Weight
497.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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