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JNJ-9676

Product Specifications

CAS Number

3026520-19-1

Target

DNA/RNA Synthesis|||SARS-CoV

Related Pathways

Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

Purity

0.9993

Bioactivity

JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, which binds to the membrane protein dimer's transmembrane domain-formed binding pocket, thereby blocking viral assembly and release. It exhibits nanomolar-level antiviral activity against the novel coronavirus and SARS-CoV.

Smiles

C(NC1=CC(C#N)=CC=C1)(=O)C2=C3N(C[C@H](C)N(C3=O)C4=CC=C(C(F)(F)C5=CC=CC=C5)C=C4)N=C2

Molecular Formula

C28H21F2N5O2

Molecular Weight

497.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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