Lonitoclax
Product Specifications
CAS Number
2952589-57-8
Target
Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
Lonitoclax is an inhibitor of B-cell lymphoma 2 (Bcl-2) . It demonstrates antitumor activity in B-cell and myeloid malignancy models comparable to Venetoclax. Lonitoclax holds potential for research in relapsed or refractory chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma, and certain low-grade lymphomas.
Smiles
C(=O)(C1=C(C=C(Cl)C=C1)C2=CC(C(N(CC3=C(C)C(OC)=CC=C3)C4=CC=C(O)C=C4)=O)=C(C)N2C)N5[C@H](CN6CCOCC6)CC=7C(C5)=CC=CC7
Molecular Formula
C43H45ClN4O5
Molecular Weight
733.294
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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