PARP/NAMPT-IN-1
Product Specifications
CAS Number
2755825-45-5
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
PARP/NAMPT-IN-1 (Compound 13j) is a dual-target inhibitor of PARP and NAMPT, with IC50 values of 0.8 nM for PARP1 and 18 nM for NAMPT. It suppresses breast cancer cell proliferation and migration, inducing apoptosis. PARP/NAMPT-IN-1 is applicable for research on triple-negative breast cancer.
Smiles
O=C(NCCCCCCN1CCN(C(=O)C2=CC(=CC=C2F)CC3=NNC(=O)C=4C=CC=CC43)CC1)C=5C=CN6C=CN=C6C5
Molecular Formula
C34H36FN7O3
Molecular Weight
609.693
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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