Urease-IN-20
Product Specifications
CAS Number
2998940-98-8
Target
Reactive Oxygen Species|||Apoptosis|||Antibacterial
Related Pathways
Apoptosis|||NF-?B|||Immunology/Inflammation|||Metabolism|||Microbiology/Virology
Bioactivity
Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 ?M for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and ?H2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.
Smiles
O=C(OC1=N[Se]C=2C=CC=CC12)C=3C=CC=C(F)C3
Molecular Formula
C14H8FNO2Se
Molecular Weight
320.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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