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Urease-IN-20

Product Specifications

CAS Number

2998940-98-8

Target

Reactive Oxygen Species|||Apoptosis|||Antibacterial

Related Pathways

Apoptosis|||NF-?B|||Immunology/Inflammation|||Metabolism|||Microbiology/Virology

Bioactivity

Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 ?M for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and ?H2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.

Smiles

O=C(OC1=N[Se]C=2C=CC=CC12)C=3C=CC=C(F)C3

Molecular Formula

C14H8FNO2Se

Molecular Weight

320.18

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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