4-Hydroxyresveratrol
Product Specifications
CAS Number
331443-00-6
Target
Bcl-2 Family, Apoptosis, MDM-2/p53
Related Pathways
Apoptosis
Bioactivity
4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene) is a resveratrol analog that variably induces the expression of pro-apoptotic genes such as p53 and Bax. It triggers apoptosis in SV40 virus-transformed WI38 cells (WI38VA), but not in WI38 cells. Additionally, 4-Hydroxyresveratrol significantly increases the expression of p53, GADD45, and Bax genes in WI38VA cells, while suppressing the expression of the bcl-2 gene.
Smiles
C(=C/C1=CC=C(O)C=C1)\C2=CC(O)=C(O)C(O)=C2
Molecular Formula
C14H12O4
Molecular Weight
244.243
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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