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EGFR/BRAFV600E-IN-4

Product Specifications

Target

Apoptosis, Raf, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, MAPK, Angiogenesis, Apoptosis

Bioactivity

EGFR/BRAFV600E-IN-4 (Compound 10f) is a dual inhibitor of EGFR and BRAFV600E, with IC50 values of 61 nM and 43 nM, respectively. It halts the cell cycle, induces apoptosis in both early and late stages, and inhibits cancer cell growth in vitro, showing broad-spectrum anticancer activity.

Molecular Formula

C22H16N4OS

Molecular Weight

384.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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