EGFR/BRAFV600E-IN-4
Product Specifications
Target
Apoptosis, Raf, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, MAPK, Angiogenesis, Apoptosis
Bioactivity
EGFR/BRAFV600E-IN-4 (Compound 10f) is a dual inhibitor of EGFR and BRAFV600E, with IC50 values of 61 nM and 43 nM, respectively. It halts the cell cycle, induces apoptosis in both early and late stages, and inhibits cancer cell growth in vitro, showing broad-spectrum anticancer activity.
Molecular Formula
C22H16N4OS
Molecular Weight
384.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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