NLRP3-IN-72
Product Specifications
CAS Number
3043952-13-9
Target
NOD-like Receptor (NLR), Pyroptosis, Interleukin, ROS
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.
Smiles
FC=1C=CC2=C(N=C(NC3=NC=4C=C(C=CC4O3)CN(C)CC)N2C)C1
Molecular Formula
C19H20FN5O
Molecular Weight
353.393
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-D450435-250MG 250 mg
(1R)-2,3-Dihydro-N-2-propen-1-yl-1H-inden-1-amine Ethanedioate
Sign In for Pricing
View Details 
BNC040942-100 1x 100 µL
Milk Fat Globulin (EDM45), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
3011C 500 µg
IPG -2 AM - yellow -green fluorescent potassium indicator
Sign In for Pricing
View Details 