Apoptosis inducer 36
Product Specifications
CAS Number
2831492-41-0
Target
Apoptosis, Pyroptosis
Related Pathways
Immunology/Inflammation, Apoptosis
Bioactivity
Apoptosisinducer 36 (Compound 42) exhibits anti-leukemic activity by reducing leukemia stem cells (LSC) and inducing differentiation. It inhibits proliferation of AML cells by causing cell cycle arrest in the G1 phase, and induces PANoptosis, which includes apoptosis, pyroptosis, and necrosis.
Smiles
C[C@@]12[C@]([C@]3([C@@](CC1)(OC(=O)C(=C)C3)[H])[H])(CC[C@@H]2O[Si](C(C)C)(C(C)C)C(C)C)[H]
Molecular Formula
C23H40O3Si
Molecular Weight
392.647
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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