Hypoxia inducer-1
Product Specifications
Target
Reactive Oxygen Species, Apoptosis, ROS
Related Pathways
Apoptosis, Metabolism, Immunology/Inflammation, NF-κB
Bioactivity
Hypoxia inducer-1 (Compound N6) is a NO donor compound that is orally active and activated under hypoxic conditions. It exhibits high selectivity in releasing NO, inhibiting apoptosis, necrosis, and elevated levels of reactive oxygen species (ROS) associated with hypoxia. It modulates vasodilation and shows protective effects in a mouse model of myocardial hypoxic injury, making it useful for coronary heart disease research.
Smiles
CN(C1=CC=C(C=C1)OCC2=CC(=C(C=C2)[N+](=O)[O-])F)N=O
Molecular Formula
C14H12FN3O4
Molecular Weight
305.261
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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