CIB-L43
Product Specifications
CAS Number
1082942-70-8
Target
TGF-beta/Smad, PTEN, Akt, DNA/RNA Synthesis
Related Pathways
Stem Cells, DNA Damage/DNA Repair, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint
Purity
0.9964
Bioactivity
CIB-L43 is a high affinity and orally available TRBP inhibitor (KD = 4.78 nM), which can effectively inhibit the biosynthesis of oncogenic miR-21, increase the expression of PTEN and Smad7, and block the AKT and TGF-β signaling pathways to inhibit the proliferation and migration of hepatocellular carcinoma (HCC) cells.
Smiles
O=C(O)C=1SC(=NC1C)C=2C=CC(=CC2)N3CCOCC3
Molecular Formula
C15H16N2O3S
Molecular Weight
304.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS8115310-01 0.3 mg
Human CKMT1A Baculovirus-Insect cells Overexpression Lysate
Sign In for Pricing
View Details MBS8115310-02 5x 0.3 mg
Human CKMT1A Baculovirus-Insect cells Overexpression Lysate
Sign In for Pricing
View Details L2601-02 50 µg
Lipoprotein Receptor, Low Density (LDLR, LDL Receptor) discontinued, see L2601-02B
Sign In for Pricing
View Details 
