CAR-2
Product Specifications
CAS Number
3030055-40-1
Target
Reactive Oxygen Species, Ferroptosis, Photosensitizer
Related Pathways
NF-κB, Apoptosis, Metabolism, Immunology/Inflammation
Bioactivity
CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LD) . It exhibits phototoxicity against breast cancer cells with an IC50 of 0.01-0.02 μM and demonstrates antitumor efficacy in a 4T1 xenograft mouse model.
Smiles
O=C(OC)C=1N=C(C2=C3C(=C(I)C(=[N]3[B+3]([F-])([F-])[N-]4C2=C(C(I)=C4C)C)C)C)C5=C(C1)C=6C=CC=CC6N5C
Molecular Formula
C27H23BF2I2N4O2
Molecular Weight
738.114
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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