BRD4 degrader-5
Product Specifications
Target
Autophagy, AUTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic, Autophagy
Bioactivity
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 μM) . It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 μM.
Molecular Formula
C35H42ClN7O2S
Molecular Weight
660.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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