UAMC-4821
Product Specifications
Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
UAMC-4821 is a ferroptosis inhibitor with an IC50 of 5.2 nM. It effectively scavenges free radicals, inhibits lipid peroxidation, and prevents ML162-induced ferroptosis, providing protective effects on HT-1080 cells. With favorable pharmacokinetic properties in mice, UAMC-4821 presents an oral bioavailability of 63% and demonstrates blood-brain barrier permeability.
Molecular Formula
C15H19N3O
Molecular Weight
257.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
043677-Biotin 200 µL
USP6, CT (USP6, HRP1, TRE2, Ubiquitin carboxyl-terminal hydrolase 6, Deubiquitinating enzyme 6, Proto-oncogene TRE-2, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6) (Biotin) discontinued
Sign In for Pricing
View Details 
VAng-Lsx09795-1mgEcoli 1 mg (E. coli)
Recombinant Shigella Sonnei iraM Protein (aa 1-107)
Sign In for Pricing
View Details 