Jun13296
Product Specifications
CAS Number
3063566-68-4
Target
Virus Protease, SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 μM, Ki = 8.8 nM) . It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.
Smiles
[C@@H](NC(=O)C1=CC(=CC=C1C)N2CC3N(C)C(C2)CC3)(C)C=4C5=C(N=C(C4)C6=CN(C)N=C6)C=CC=C5
Molecular Formula
C30H34N6O
Molecular Weight
494.631
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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