What is the catalog number for NF-κB-IN-19?

The catalog number for NF-κB-IN-19 is T205560.

What sizes are available for NF-κB-IN-19?

NF-κB-IN-19 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NF-κB-IN-19 come in?

NF-κB-IN-19 is available in 2 different pack sizes.

Is NF-κB-IN-19 in stock?

NF-κB-IN-19 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NF-κB-IN-19?

NF-κB-IN-19 is manufactured by Molfinity.

What is the estimated delivery time for NF-κB-IN-19?

Estimated delivery time for NF-κB-IN-19 is approximately 10 business day(s), depending on your location.

NF-κB-IN-19

Product Specifications

Target

ROS, PI3K, STAT, HIF/HIF Prolyl-Hydroxylase, Autophagy, Apoptosis, Reactive Oxygen Species, Akt, NF-κB

Related Pathways

JAK/STAT signaling, Metabolism, Cytoskeletal Signaling, Stem Cells, Immunology/Inflammation, Autophagy, NF-κB, PI3K/Akt/mTOR signaling, Apoptosis, Chromatin/Epigenetic

Bioactivity

NF-κB-IN-19 (Compound 8) is an NF-κB inhibitor. It effectively induces DNA damage in tumor cells through the NF-κB signaling pathway and promotes the production of reactive oxygen species (ROS), as well as induces autophagy and apoptosis. Additionally, NF-κB-IN-19 inhibits levels of VEGF and HIF-1α, exerting antiproliferative effects in tumor cells through the PI3K/AKT and STAT-3 pathways. It is also effective in overcoming cisplatin resistance and exhibits antitumor activity.