PROTAC HDAC6 degrader 4
Product Specifications
Target
PROTACs|||HDAC
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||PROTAC
Bioactivity
PROTAC HDAC6 degrader4 (Compound 17c) is a PROTAC that targets and degrades HDAC6, with a DC50 of 14 nM. It exhibits inhibitory activity against HDAC1, HDAC2, HDAC3, and HDAC6, with IC50 values of 2.2, 2.37, 0.61, and 0.295 ?M, respectively. [Pink: ligand for target protein HDAC6 ligand-3; Black: linker; Blue: ligand for cereblon E3 ligase]
Molecular Formula
C39H42FN9O7
Molecular Weight
767.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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