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CDK9-IN-36

Product Specifications

Target

CDK, Apoptosis

Related Pathways

Cell Cycle/Checkpoint, Apoptosis

Bioactivity

CDK9-IN-36 (Compound T7) is a potent, selective, and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. It effectively suppresses the proliferation of Osimertinib-resistant NSCLC cells by downregulating Mcl-1, reducing colony formation, and inducing apoptosis. Additionally, CDK9-IN-36 exhibits antitumor activity in xenograft models.

Molecular Formula

C30H33F2N5O4

Molecular Weight

565.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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