ALT-007
Product Specifications
CAS Number
2035010-37-6
Target
Acyltransferase
Related Pathways
Metabolism
Bioactivity
ALT-007 is an orally bioavailable inhibitor of serine palmitoyltransferase (SPT), the rate-limiting enzyme in de novo ceramide synthesis. In murine models of age-related sarcopenia, ALT-007 effectively restores muscle mass and function impaired by aging. Additionally, ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and in mouse models of aging and age-associated diseases, acting as a ceramide inhibitor.
Smiles
O=C(NC1C2=C(C=NN2C(C)C)N(C(=O)C3=CN=C(OC)C(OC)=C3)CC1)C=4C=CC=CC4OC(F)(F)F
Molecular Formula
C25H26F3N5O5
Molecular Weight
533.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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