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SIRT-IN-7

Product Specifications

CAS Number

1620634-65-2

Target

Apoptosis, MDM-2/p53, Autophagy, Sirtuin

Related Pathways

Chromatin/Epigenetic, Apoptosis, Autophagy, DNA Damage/DNA Repair

Bioactivity

SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. It effectively suppresses the expression of SIRT1, SIRT2, and SIRT3, leading to increased acetylation and activation of p53. Additionally, SIRT-IN-7 inhibits the proliferation of breast cancer cells and induces apoptosis and autophagy, demonstrating antitumor activity.

Smiles

ClC=1C=CC=2N=C(SC2C1)NC(C3=CC=C(Br)C=C3)C4=C(O)C=CC=5C=CC=CC54

Molecular Formula

C24H16BrClN2OS

Molecular Weight

495.819

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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