SIRT-IN-7
Product Specifications
CAS Number
1620634-65-2
Target
Apoptosis|||MDM-2/p53|||Autophagy|||Sirtuin
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Autophagy|||DNA Damage/DNA Repair
Bioactivity
SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. It effectively suppresses the expression of SIRT1, SIRT2, and SIRT3, leading to increased acetylation and activation of p53. Additionally, SIRT-IN-7 inhibits the proliferation of breast cancer cells and induces apoptosis and autophagy, demonstrating antitumor activity.
Smiles
ClC=1C=CC=2N=C(SC2C1)NC(C3=CC=C(Br)C=C3)C4=C(O)C=CC=5C=CC=CC54
Molecular Formula
C24H16BrClN2OS
Molecular Weight
495.819
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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