What is the catalog number for Scr-IN-1?

The catalog number for Scr-IN-1 is T205472.

What sizes are available for Scr-IN-1?

Scr-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Scr-IN-1 come in?

Scr-IN-1 is available in 2 different pack sizes.

Is Scr-IN-1 in stock?

Scr-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Scr-IN-1?

Scr-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for Scr-IN-1?

Estimated delivery time for Scr-IN-1 is approximately 10 business day(s), depending on your location.

Scr-IN-1

Product Specifications

Target

Apoptosis, Src

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

Bioactivity

Scr-IN-1 (Compound 4e) is a tyrosine kinase inhibitor demonstrating inhibitory activity against HCT-116 and MIA-PaCa-2 cells, with IC50 values of 0.16 μM and 1.16 μM, respectively. It shows selectivity towards HCT-116 cells and MIA-PaCa-2 cells, with a selectivity index (SI) greater than 625 and 86. Scr-IN-1 induces apoptosis in HCT-116 colon cancer cells without altering the proportion of necrotic cells and is a potential novel SRC kinase inhibitor for HCT-116 cells. This compound is suitable for cancer research.