MP-010

Product Specifications

CAS Number

3024617-59-9

Target

FKBP|||Calcium Channel

Related Pathways

Membrane transporter/Ion channel|||Autophagy|||Metabolism|||Immunology/Inflammation|||Apoptosis

Bioactivity

MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.