PRMT5-IN-48
Product Specifications
CAS Number
2640287-77-8
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
PRMT5-IN-48 (compound D3) is an orally active PRMT5 inhibitor with an IC50 of 20.7 nM, displaying antitumor activity. It effectively suppresses the growth of various cancer cells, induces apoptosis, and causes cell cycle arrest at the G0/G1 phase. PRMT5-IN-48 is applicable for research in non-Hodgkin's lymphoma (NHL) .
Smiles
C([C@@H](CN1CC=2C(CC1)=CC=CC2)O)N3CC4(C=5C(C3=O)=CC(NC6CC7(C6)CN(C(C)=O)C7)=NC5)CC4
Molecular Formula
C30H37N5O3
Molecular Weight
515.646
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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