FMP
Product Specifications
Target
ROS, Apoptosis, Reactive Oxygen Species, PARP, Caspase, Bcl-2 Family, MDM-2/p53
Related Pathways
Proteases/Proteasome, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic, Metabolism, Immunology/Inflammation, NF-κB
Bioactivity
FMP is a platinum (IV) complex. It significantly upregulates the expression of γ-H2AX and p53, enhances ROS production, and markedly increases the expression of apoptosis (Apoptosis) related proteins (DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax) . FMP exhibits antiproliferative activity against breast cancer.
Molecular Formula
C18H18Cl2N2O7Pt
Molecular Weight
640.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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