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HDAC-IN-85

Product Specifications

Target

DNA/RNA Synthesis, HDAC

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.

Molecular Formula

C24H27FN4O5

Molecular Weight

470.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

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