HDAC-IN-85
Product Specifications
Target
DNA/RNA Synthesis, HDAC
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.
Molecular Formula
C24H27FN4O5
Molecular Weight
470.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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