PD-L1/VISTA-IN-2
Product Specifications
Target
PD-1/PD-L1
Related Pathways
Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint
Bioactivity
PD-L1/VISTA-IN-2 (Compound S8) is an orally active dual inhibitor targeting PD-L1 and VISTA, with an IC50 of 1.4 ?M for PD-L1 and a KD of 2.1 ?M for VISTA. This compound can activate the tumor immune microenvironment, exerting anticancer effects.
Molecular Formula
C22H22N2O3
Molecular Weight
362.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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