PD-L1/VISTA-IN-2

Product Specifications

Target

PD-1/PD-L1

Related Pathways

Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint

Bioactivity

PD-L1/VISTA-IN-2 (Compound S8) is an orally active dual inhibitor targeting PD-L1 and VISTA, with an IC50 of 1.4 ?M for PD-L1 and a KD of 2.1 ?M for VISTA. This compound can activate the tumor immune microenvironment, exerting anticancer effects.

Molecular Formula

C22H22N2O3

Molecular Weight

362.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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