What is the catalog number for HDAC1-IN-9?

The catalog number for HDAC1-IN-9 is T205384.

What sizes are available for HDAC1-IN-9?

HDAC1-IN-9 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does HDAC1-IN-9 come in?

HDAC1-IN-9 is available in 2 different pack sizes.

Is HDAC1-IN-9 in stock?

HDAC1-IN-9 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HDAC1-IN-9?

HDAC1-IN-9 is manufactured by Molfinity.

What is the estimated delivery time for HDAC1-IN-9?

Estimated delivery time for HDAC1-IN-9 is approximately 10 business day(s), depending on your location.

HDAC1-IN-9

Product Specifications

Target

HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

HDAC1-IN-9 (13c) is an HDAC1 inhibitor. It inhibits the HDAC1 enzyme with an IC50 value of 1.07 μM. This compound exhibits the strongest antiproliferative activity against HT-29 (human colon adenocarcinoma cells), with an IC50 of 1.78 μM. In HCT-116 (human colon cancer cells), HDAC1-IN-9 significantly induces apoptosis. Additionally, HDAC1-IN-9 possesses antiangiogenic properties, reducing the expression levels of VEGFR-2 and phosphorylated VEGFR-2 (pVEGFR-2) by approximately 80%.