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Proteasome-IN-7

Product Specifications

Target

Proteasome

Related Pathways

Ubiquitination, Proteases/Proteasome

Bioactivity

Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.

Molecular Formula

C48H56N6O10S

Molecular Weight

909.06

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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