CDK2-IN-41
Product Specifications
Target
Apoptosis|||Reactive Oxygen Species|||ROS|||CDK
Related Pathways
Apoptosis|||Immunology/Inflammation|||NF-?B|||Cell Cycle/Checkpoint|||Metabolism
Bioactivity
CDK2-IN-41 (Compound 7a) is a CDK2 inhibitor that impedes the cell cycle by binding to CDK2, leading to cytotoxicity, increased ROS production, and apoptosis (Apoptosis) . It exhibits anticancer activity with an IC50 of 10 µM against acute myeloid leukemia (AML) HL-60 cells. CDK2-IN-41 is applicable in research related to AML-associated cancers.
Molecular Formula
C19H21N3S
Molecular Weight
323.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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