ErSO-TFPy
Product Specifications
CAS Number
3035547-78-2
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ER?+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.
Smiles
O=C1[C@@](C=2C(N1)=C(C(F)(F)F)C=CC2)(N3CC(F)(F)C(F)(F)C3)C4=CC=C(O)C=C4
Molecular Formula
C19H13F7N2O2
Molecular Weight
434.307
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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