SHP1 activator 1
Product Specifications
Target
Phosphatase|||Apoptosis|||STAT
Related Pathways
JAK/STAT signaling|||Apoptosis|||Stem Cells|||Metabolism
Bioactivity
SHP1 activator 1 (Compound 3n) is an activator of protein tyrosine phosphatase 1 containing the src homology-2 domain (SHP1), with an EC50 of 17.66 ?M. It inhibits the proliferation of ABC-DLBCL cells and induces apoptosis by suppressing the STAT3 signaling pathway. In MDA-MB-231 cells, SHP1 activator 1 emits blue and green fluorescent signals, making it suitable as a cellular imaging agent.
Molecular Formula
C27H34N4O4
Molecular Weight
478.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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