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SHP1 activator 1

Product Specifications

Target

Phosphatase, Apoptosis, STAT

Related Pathways

JAK/STAT signaling, Apoptosis, Stem Cells, Metabolism

Bioactivity

SHP1 activator 1 (Compound 3n) is an activator of protein tyrosine phosphatase 1 containing the src homology-2 domain (SHP1), with an EC50 of 17.66 μM. It inhibits the proliferation of ABC-DLBCL cells and induces apoptosis by suppressing the STAT3 signaling pathway. In MDA-MB-231 cells, SHP1 activator 1 emits blue and green fluorescent signals, making it suitable as a cellular imaging agent.

Molecular Formula

C27H34N4O4

Molecular Weight

478.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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