PRC1-IN-1
Product Specifications
CAS Number
2396639-29-3
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
PRC1-IN-1 (compound RB-4) is an inhibitor of the polycomb repressive complex 1 (PRC1) with an IC50 of 2.3 μM. It targets RING1B-BMI1, RING1A-BMI1, and RING1B-PCGF1, exhibiting IC50 values of 2.8 μM, 2.6 μM, and 1.8 μM, respectively.
Smiles
O=C(O)C=1NC(C=2C=C(F)C=C3NC=CC32)=C(C1C=4C(Cl)=CC=C5NC=CC54)C(C)C
Molecular Formula
C24H19ClFN3O2
Molecular Weight
435.878
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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