D3/5-HT receptor modulator-1
Product Specifications
CAS Number
898532-85-9
Target
Dopamine Receptor, 5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.
Smiles
O=C(NCCCCN1CCN(C2=CC=CC(=C2)C)CC1)C=3OC=4C=CC=CC4C3
Molecular Formula
C24H29N3O2
Molecular Weight
391.506
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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