JPHM-2-167
Product Specifications
CAS Number
1258877-17-6
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
PHM-2-167 (Compound 11) is a selective inhibitor of the prolyl hydroxylase domain enzyme (PHD) . It inhibits PHD2 and PHD3 with IC50 values of 0.253 μM and 3.95 μM, respectively. PHM-2-167 is applicable for research in chronic kidney disease.
Smiles
O=C1N(C=2C=CC(=CC2)C=3C=CC=CC3)C(=O)C4(N1C5=NC=CC=N5)CCN(CC6=NC=CC=C6C)CC4
Molecular Formula
C30H28N6O2
Molecular Weight
504.582
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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