(S) -WSD0628
Product Specifications
CAS Number
2765449-10-1
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Bioactivity
(S) -WSD0628 is the S isomer of WSD0628 and serves as an ATM inhibitor, effectively suppressing ATM phosphorylation in MCF-7 cells with an IC50 of less than 100 nM. This compound also demonstrates radiosensitizing activity and is capable of penetrating the blood-brain barrier.
Smiles
O=C1N(C=2C=3C(N=CC2N1C)=CC=C(C3)C=4C=CC(OC)=NC4)[C@@H]5C(F)(F)CN(C)CC5
Molecular Formula
C23H23F2N5O2
Molecular Weight
439.458
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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