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KRASG12C IN-16

Product Specifications

Target

Kras, Apoptosis, p38 MAPK, mTOR, PI3K, Ras

Related Pathways

Apoptosis, GPCR/G Protein, MAPK, PI3K/Akt/mTOR signaling

Bioactivity

KRASG12C IN-16 (Compound SK-17) is a selective, covalent, and orally active KRASG12C inhibitor. It can induce apoptosis and effectively prevent the activation of the MAPK and PI3K/mTOR signaling pathways. Additionally, KRASG12C IN-16 exhibits antitumor activity against pancreatic cancer.

Molecular Formula

C28H35ClN8O2

Molecular Weight

551.08

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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