KRASG12C IN-16
Product Specifications
Target
Kras, Apoptosis, p38 MAPK, mTOR, PI3K, Ras
Related Pathways
Apoptosis, GPCR/G Protein, MAPK, PI3K/Akt/mTOR signaling
Bioactivity
KRASG12C IN-16 (Compound SK-17) is a selective, covalent, and orally active KRASG12C inhibitor. It can induce apoptosis and effectively prevent the activation of the MAPK and PI3K/mTOR signaling pathways. Additionally, KRASG12C IN-16 exhibits antitumor activity against pancreatic cancer.
Molecular Formula
C28H35ClN8O2
Molecular Weight
551.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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