KRASG12C IN-16
Product Specifications
Target
Kras|||Apoptosis|||p38 MAPK|||mTOR|||PI3K|||Ras
Related Pathways
Apoptosis|||GPCR/G Protein|||MAPK|||PI3K/Akt/mTOR signaling
Bioactivity
KRASG12C IN-16 (Compound SK-17) is a selective, covalent, and orally active KRASG12C inhibitor. It can induce apoptosis and effectively prevent the activation of the MAPK and PI3K/mTOR signaling pathways. Additionally, KRASG12C IN-16 exhibits antitumor activity against pancreatic cancer.
Molecular Formula
C28H35ClN8O2
Molecular Weight
551.08
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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