TCF4/β-catenin-IN-1
Product Specifications
Target
Wnt/beta-catenin, Cytochromes P450, Apoptosis, Bcl-2 Family, Caspase, MDM-2/p53
Related Pathways
Apoptosis, Proteases/Proteasome, Cytoskeletal Signaling, Metabolism, Stem Cells
Bioactivity
TCF4/β-catenin-IN-1 (Compound 8b) is an inhibitor of TCF4/β-catenin that induces apoptosis. This compound enhances the expression of p53, caspase-3, caspase-8, caspase-9, and Bax proteins, while reducing Bcl-2 protein levels. TCF4/β-catenin-IN-1 also inhibits CYP3A4, CYP1A2, and CYP2C19, demonstrating significant cytotoxic activity in cancer cells.
Molecular Formula
C23H15N7O3
Molecular Weight
437.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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