Antidepressant agent 8
Product Specifications
CAS Number
3066104-04-6
Target
IGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.
Smiles
O=C(NCC1CCCCC1)CSC2=NN=C(S2)NCC=3C=CC=C(F)C3
Molecular Formula
C18H23FN4OS2
Molecular Weight
394.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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