AUR1545
Product Specifications
CAS Number
3031593-79-7
Target
Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9884
Bioactivity
AUR1545 is a selective KAT2A/KAT2B degradator exhibiting inhibitory activity against cancer models including AML, SCLC, and NEPC, and suppressing tumour growth in the NCI-H1048 xenograft model.
Smiles
O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5CCN(C(=O)C6=CC=C(C=C6)[C@H]7C[C@@H](NC8=C(Br)C(=O)N(C)N=C8)CN(C)C7)CC5)CC4
Molecular Formula
C41H50BrN9O5
Molecular Weight
828.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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