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AUR1545

Product Specifications

CAS Number

3031593-79-7

Target

Histone Acetyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9884

Bioactivity

AUR1545 is a selective KAT2A/KAT2B degradator exhibiting inhibitory activity against cancer models including AML, SCLC, and NEPC, and suppressing tumour growth in the NCI-H1048 xenograft model.

Smiles

O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5CCN(C(=O)C6=CC=C(C=C6)[C@H]7C[C@@H](NC8=C(Br)C(=O)N(C)N=C8)CN(C)C7)CC5)CC4

Molecular Formula

C41H50BrN9O5

Molecular Weight

828.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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